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Amino linker phosphoramidites from Bioneer

For 5’-/3’-end or internal functionalization during oligo synthesis

Overview
Ordering Information

Features of Amino linkers

Amino linker products can be coupled with standard synthesis protocols, such as DNA monomer phosphoramidite coupling protocols.
The primary amino group can be used for subsequent conjugation of a variety of reporter dyes or labels.
The base-labile TFA-group is easily cleaved with concentrated ammonia during the cleavage and deprotection steps. Additional deprotection steps are not necessary.
The DMT-group can be cleaved more conveniently than the MMT-group on the synthesis instrument with an acidic deblocking solution to enable on-support labeling protocols.
The 5'-DMT amino linker can be treated with normal deprotection and cleavage methods.