Amino linker phosphoramidites from Bioneer
For 5’-/3’-end or internal functionalization during oligo synthesis
Overview
Ordering Information
Features of Amino linkers
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Amino linker products can be coupled with standard synthesis protocols, such as DNA monomer phosphoramidite coupling protocols. |
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The primary amino group can be used for subsequent conjugation of a variety of reporter dyes or labels. |
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The base-labile TFA-group is easily cleaved with concentrated ammonia during the cleavage and deprotection steps. Additional deprotection steps are not necessary. |
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The DMT-group can be cleaved more conveniently than the MMT-group on the synthesis instrument with an acidic deblocking solution to enable on-support labeling protocols.
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The 5'-DMT amino linker can be treated with normal deprotection and cleavage methods. |