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In vivo siRNA delivery using SAMiRNA Custom Service

SAMiRNA Custom Services, a complete solution for gene function analysis and target discovery and validation through in vivo siRNA studies

Overview
Technical/Specs
Literature/Support
Ordering Information

Custom Designed SAMiRNA Order From

Bioneer’s SAMiRNA Custom Services will be provided through a SAMiRNA ordering system with comprehensive service packages at highly competitive prices. Please let us know the details of your project, so that we can provide you with an accurate quotation and timeline estimate


SAMiRNA ordering

SAMiRNAs are synthesized by incorporating siRNA sequences into SAMiRNA platform. siRNA sequences can be picked from either custom siRNAs or Bioneer’s pre-designed siRNA pool .

1. Custom siRNA (link to ordering form)
SAMiRNAs loaded with customized siRNAs are available. Please let us know a sequence of your own functional anti-sense strand. SAMiRNA nano-particle of duplex annealed with a corresponding complementary sequence will be provided.

2. Pre-designed siRNA (link to ordering form)
Pre-designed siRNA sequences for SAMiRNA synthesis can be searched in the Bioneer AccuTarget Pre-designed siRNA database by Gene ID, Symbol, Synonyms, Description and/or Accession numbers.

3. SAMiRNA controls (link to ordering form)
Varieties of SAMiRNA controls are available to confirm the functional activities and/or the delivery of SAMiRNA to target tissues. SAMiRNAs constituted with siRNA sequences aiming at non-target (negative control), GFP and luciferase are provided. In addition, SAMiRNAs can be labeled with various fluorescent dyes to detect the localization of SAMiRNA in vivo animal models.

  • The formation of SAMiRNA nano-particle will be guaranteed upon re-suspension by providing QC data regarding the size and PDI information of the nano-particle.

SAMiRNA Order scale of SAMiRNA (nmole) Number of mouse
(intravenous injections)
Price
Custom Designed SAMiRNA   100   5mg/kg -> 5 mouse
  1mg/kg -> 25 mouse
  Inquiring Only
  500   5mg/kg -> 25 mouse
  1mg/kg -> 125 mouse
  1000   5mg/kg -> 50 mouse
  1mg/kg -> 250 mouse
Control SAMiRNA   100   5mg/kg -> 5 mouse
  1mg/kg -> 25 mouse
  Inquiring Only
  500   5mg/kg -> 25 mouse
  1mg/kg -> 125 mouse
  1000   5mg/kg -> 50 mouse
  1mg/kg -> 250 mouse
Fluorescence conjugated SAMiRNA

(FITC, Cy5.5 etc)
  100   5mg/kg -> 5 mouse
  1mg/kg -> 25 mouse
  Inquiring Only
  500   5mg/kg -> 25 mouse
  1mg/kg -> 125 mouse
  1000   5mg/kg -> 50 mouse
  1mg/kg -> 250 mouse